Interview with Dr. Massimo Collice, head of the NS Dept at Niguarda Hospital, the main public hospital in Milan, and a look into the brand new Gamma knife department. The Leksell Gamma Knife is a radiosurgical tool used for non-invasive treatment of brain diseases. "Gamma Knife" means that gamma rays are used to obtain a surgical effect. It is based on the stereotactic technology whoch allows to reach a target like a tumor with submillimetrical accuracy while sparing the surrounding healthy tissue. Over half million people have been treated in more than 250 centers worldwide and in 5 centers in Italy. Main indications are Arterovenous Malformations, Benign Tumors like Acoustic Neuromas, Pituitary Adenomas, Meningiomas, Methastases, Trigeminal Neuralgia and in some cases Epilepsy.